**6. The prevention of adhesions and the use of adhesion barriers**

Adhesion barriers are adjuvants for peritoneal administration that can reduce adhesion formation [18]. Anti-adhesive material used to prevent adhesion formation, especially in patients who already have intraperitoneal adhesions from previous surgery, pelvic inflammatory disease, or endometriosis [16]. There are several forms of adhesion barriers: solid membranes, gels, and liquids. Adhesion barrier act as a

spacer that separates injured surfaces of the peritoneum, allowing these surfaces to heal without forming fibrinous attachment, which eventually leads to adhesions. Barriers should be inert to the human immune system and be slowly degradable. Adhesion barriers might also be used to prevent recurrence after surgical treatment. The most common applied adhesion barriers and their impact on adhesion formation are described below [8]:

