**Abstract**

Despite the advantages of gasification over combustion, some elements remain to improve. Fortunately, it is not necessary to reinvent the wheel to improve efficiency and quality because there are already methodologies that have been proven successful with other processes, like the Six Sigma DMAIC methodology. Therefore, this chapter explores the synergies between gasification and Six Sigma DMAIC to improve gas quality and hydrogen production, using RDF and wood as feedstock. Furthermore, the blends and equivalence ratio influence the produced gas is explored.

**Keywords:** Six Sigma, DMAIC, refuse-derived fuels, gasification, biomass
