**4. Conclusion**

Acetylcholine, being a part of cholinergic system, is a neurochemical and capable of performing plethora of functions in brain and human body. In addition to manage *Role of Acetylcholine in Chronic Diseases DOI: http://dx.doi.org/10.5772/intechopen.110663*

the sympathetic, para-sympathetic and autonomic functions, its role in chronic diseases has been well understood and reviewed comprehensively. Furthermore, the cholinergic system, it's projections and the cognitive role has been discussed along with a brief overview of cholinergic receptors. Also, the influence of acetylcholine on different types of chronic diseases including cardiovascular diseases, neurodegenerative disorders and metabolic diseases has been illustrated in detail. In last, the therapeutic section has been presented, covering the insights on agonist and antagonists of Acetylcholine for understanding better treatment options.
