**Acknowledgements**

I Dr. Saurabh Krishna Misra would like to express my special thanks to my wife Dr. Richa Dokania Pedodontist for her constant encouragement thought the journey and Dr. Ankita (co Author) for her support and valuable suggestions in the preparation of this chapter.

Dr. Ankita Pundir, would like to express my humble gratitude to Dr. Saurabh K Misra (the author) for giving me the opportunity to work on this chapter and for investing his belief in me. I hope I have done my part as per his expectations. I would also like to thank my beloved husband, Dr. Aakash Kumar Singh who is a budding rheumatologist, for his inputs and help in developing this chapter.

we also thank Marica Novakovic for being empathetic towards our personal aspects affecting the submission deadline of this chapter and for offering help all along.
