*2.3.5 CT795*

The Chlamydia-specific protein CT795 is detected in the cytoplasm of infected host cells via a sec-dependent mechanism and not by a type III secretion pathway [4].

## *2.3.6 C. trachomatis glycogen synthase (GlgA)*

In recent studies, chlamydial GlgA seems to appear in host cell cytosol and chlamydial inclusion lumen among all *C. trachomatis* serovars and is immunogenic in women urogenital infections. Its specific role in the pathogenicity of chlamydial infections still needs to be elucidated but seems to interfere with the accumulation of glycogen, within the inclusion lumen [17]. Glycogen is a nutritional source but also a TLR2 ligand. In *Chlamydia muridarum* infection plasmid dependent TLR2 activation is related to the promotion of infection and the chronic pathology of oviduct inflammation [18].
