*2.4.1 Dialysis-associated hypoxemia*

During dialysis arterial PaO2 decreases by 5–20 mmHg reaching nadir at 30–60 minutes then resolves within 60–120 minutes after discontinuation of dialysis. This is usually of no significance unless patient has pre-existing cardiopulmonary disease [14].

In high-risk patients, preventive measures include intradialytic use of oxygen, conventional bicarbonate dialysate, and biocompatible membranes. Further optimizing haematocrit and performing sequential isolated UF followed by HD may reduce the likelihood of hypoxemia.
