**7. Conclusions**

Co-crystallization is a promising approach for improving the physicochemical properties of APIs. For years the research fraternity has worked tirelessly to develop numerous methodologies for the preparation of pharmaceutically acceptable cocrystals. The co-crystallization protocol includes lab-scale synthetic methodology as well as large-scale production methods. In the current chapter, we have aimed to provide standard descriptions and various examples of established and emerging co-crystal preparations in context of nutraceutical co-crystals. Also in the chapter, we have provided detailed insight into the proposed mechanisms of co-crystallization in different techniques. As co-crystals continue to gain interest and prove their value, the range of demonstrated co-crystal application areas continues to expand. The current chapter also highlights the increasing application of pharmaceutical co-crystals. It is anticipated that co-crystals will become more and more routine in pharmaceutical development as their benefits continue to be demonstrated and routine routes of manufacturing are proven. Since the early 2000s, it was realized that cocrystal engineering may be a potential approach to improve the physicochemical properties of pharmaceuticals, which was contributed to several representative pharmaceutical cocrystal publications. In conclusion, the current chapter emphasizes the role of crystal engineering in pharmaceutical-based cocrystal design. Also by virtue of the current chapter the authors encourage researchers to explore the possibility of creating novel nutraceutical co-crystal for bringing naturally occurring molecules to the forefront of drug designing and development paradigms.

*Co-Crystallization Techniques for Improving Nutraceutical Absorption and Bioavailability DOI: http://dx.doi.org/10.5772/intechopen.109340*
