**6. Conclusion and outlook**

Though co-crystallization is a critical technique of improving therapeutic potential of pharmaceutically poor APD-APIs, there are several changes associated with APD-APIs

co-crystal production including identification of suitable coformers and appropriate methods of production. However, like any other co-crystals, APD-APIs co-crystals are presumed to improve physical and pharmaceutical properties of ADP-APIs. APD-APIs such as phenolic acids and terpenoids have been shown to provide important functional groups, which allows for the formation of non-covalent intermolecular associations with a number of coformers during co-crystallization processes. In this chapter, information on pharmaceutical applications of APD-APIs co-crystals is summarized. With more research and clinical studies, co-crystallization of APD-APIs into single and multicomponent molecules could provide the basis for malaria treatment.
