**7. Conclusion**

Light has been used in medicine since ancient times, extending up in the form of PDT these days. Malignant cells can be killed quickly and efficiently by combining the three nontoxic aforementioned components. In the presence of molecular oxygen, porphyrinoids with the ability to localize inside the target tissue, NIR region light with deeper tissue penetration will effectively produce necrosis and apoptosis. The main advantage of this modality is that it seems to be highly adaptable to individualized treatment. The disadvantage of the therapy is that it destroys normal vegetative cells, causing the patient to become light-sensitive. This issue can be mitigated by using a more site-specific and targeted drug delivery method. Targeting can be accomplished using both passive and active mechanisms via appropriate nanoformulations. The PDT is becoming more popular among millennials due to its ease of use and faster healing time. Acne treatment with PDT is gaining more demand because it does not leave scars and aids in the fading of acne scars. The discovery of novel and effective photosensitizers with theranostic applications will improve PDT's efficacy in disease prevention, diagnosis, and monitoring. Targeted delivery with PDT is an uncharted territory that can only be carved out by a formulation scientist.

## **Conflict of interest**

The authors declare no conflict of interest.
