Metal-Based Nanomaterials Photodynamic Action with a Focus on Au and Ag Nanomaterials

*Atiyeh Nomani, Anvarsadat Kianmehr, Shahriyar Abdoli and Siamak Javani*

## **Abstract**

Photodynamic action is the interaction between cells and oxygen, light, and chemical reagent (photosensitizers). Photodynamic techniques include photodynamic diagnosis (PDD), fluorescence-guided tumor resection, and photodynamic therapy (PDT). PDD and PDT have the exact mechanism. They are based on light and tissue interaction with a difference. PDT is along with the destruction of the lesion against PDD that the diagnosis is made without destruction. Photosensitizers (PSs) could be organic and inorganic. Metal-based PSs were considered, due to the disadvantages of organic PSs such as low quantum yield and small stock shift, and high toxicity. We have examined the metal-based nanomaterials PDT in recent years. The titles considered are including the introduction that consists of explanations about photodynamic action, PDD, PDT and history of PDT, PDT mechanism, PDT effects on the immune system, photosensitizers, and metal-based nanomaterials in the photodynamic application, which this section addresses along with the application of metal nanomaterials (with a focus on gold and silver nanomaterials) in photodynamic techniques.

**Keywords:** photodynamic, metal nanomaterials, photosensitizers, gold nanoparticles, silver nanoparticles
