**2.6 Applications of LS technique**

#### *2.6.1 Dissolution and solubility enhancement*

To overcome the limited solubility of drugs in pharmaceutical area, these are formulated as LS tablets. Basically, the method of preparation of LS tablets and the effect of various formulation and processing variables on the preparation and release properties of LS tablets are studied. This technique is proved and successfully applied for low dose drugs up to 50 mg only. In case of LS tablet, formulation of high dose water insoluble drugs is a limitation. Furthermore, by adding materials like PVP to liquid medications, only a small amount of carrier is needed to generate a dry powder with good flow ability and compatibility.
