*1.7.7 Mechanical properties enhancement (Tablatability)*

Because of its numerous technical and economic advantages, tablets are the most commonly used pharmaceutical dosage form. Among these advantages are low manufacturing costs, high production throughput, ease of consumption, storage and handling. Several deficiencies caused by poor flowability and mechanical properties, on the other hand, have always been a challenge in the path to successful tablet production [124]. Some of these techniques include adding silicon dioxide to improve tablet mechanical strength and magnesium stearate to improve flowability. Co-crystallization has also been studied as a technique for improving the chemical and physical properties of powders, such as mechanical strength and flow properties [125]. Co-crystallization with theophylline, oxalic acid, naphthalene and phenazine conformers, for example, improved the compression properties of paracetamol form I [126].
