**1. Introduction**

The septic shock syndrome has been known since ancient times. With a mortality rate of about 30–45%, it is one of the biggest issues in the medical industry because it affects both community members and hospitalized patients. International guidelines are published by the scientific community for the proper diagnosis and therapeutic care of sepsis patients, such as the "Surviving Sepsis Campaign" in 2012 [1].

The hemodynamic stabilization of the patient is crucial accordingly with the guidelines, the right medication in the right time, primarily antibiotics [2].

In sepsis, the immune response of the host, or the organism, plays a crucial role. According to William Osler (1849–1919), "Except in a few cases, patients die because of their organism's response to the infection and not because of the illness." This revelation marked a turning point in our knowledge of how an infection affects the host's immune system [3].
