**5.2 Dermis**

It is divided into two different regions: the upper papillary dermis and the lower reticular dermis. The papillary dermis is located just below the dermo-epidermal junction and has conical forms called dermal papillae, and these dermal papillae interdigitate with the network of epidermal crests, increasing the interface between dermis and epidermis.

The dermis is made up, especially, of blood vessels and nerve endings. Type I and III collagen fibers, fibroblasts, fibrocytes, fibroblasts, and elastic fibers, which maintain the tension and elasticity of the skin. It also contains the sweat glands and the base of the pilosebaceous system [8].
