**Parallelism test in bioassay curves**

To test for Parallelism in the Bioassay results, curves were plotted from the Net OD at 490 nm against the log of the concentration (ng/mL). The curves were fitted with a Logistic 4PL fit and a Parallelism test was run between all the possible combinations of curves. A Parallelism F-test where the Prob > F was ≤0.05 means there is no parallelism and therefore the samples are statistically different from each other.
