**Acknowledgements**

K.S. was supported by a Grant-in-Aid for Scientific Research (C) (21 K11472) from the Ministry of Education, Culture, Sports, Science and Technology, Japan. S.S. was funded by the Brain & Behavior Research Foundation (NARSAD Young Investigator Grant, 28681) and start-up funds from Texas A&M University. We would like to express our deepest gratitude to Dr. Takako Kizaki (Visiting Professor, Kyorin University Faculty of Medicine, Mitaka, Japan) and Dr. Kazuhiko Imaizumi (Professor Emeritus, Faculty of Human Sciences, Waseda University, Tokorozawa, Japan) for their consistent guidance on macrophage biology and physiological science, respectively. The figure was created using BioRender.com.
