**6. Phagosome maturation**

The newly formed phagosome changes its membrane composition very fast to become a microbicial vacuole called the phagolysosome. The process used to transfer endocytosed material from endosomes to lysosome is complex and has been described hypothetically to explain the process of phagolysosome formation [33]. Phagosome maturation can be divided into three stages namely early phagosome late phagosome and phagosome.
