**8. Conclusions**

In this chapter, we show the complexity of phagocytosis from the clue particle recognition going through physicochemical characteristics between macrophage and the target particle to the development of the phagolysosome. Phagocytosis is not as simple as it sounds, even though we know the types of immune responses promoted by the macrophage; recent research shows that the variability may be wider. That is why more research is required to broaden the knowledge of phagocytosis, which will help improve patient's clinical conditions.
