**7. Conclusions**

The overview provided in this chapter offers a starting point into the discussion on prophylactic treatment for retinal detachments in patients with Stickler syndrome. While the evidence for prophylactic treatment of patients with Stickler syndrome is mounting, there is no prospective randomized controlled trial clearly demonstrating this benefit. There are significant challenges to a prospective trial as previously discussed in this chapter including how rare Stickler syndrome is, the varying prevalence of RD depending on subtype, and variations in treatment approach even with the treatment modality. In the interim, this overview can guide ophthalmologists in the treatment of initial management of Stickler syndrome patients.
