**12. Mortality and outcome**

Heat stroke patients' outcomes depend on early diagnosis, early cooling, and prevention and treatment of organ dysfunction. These patients are at higher risk compared to the control group for myocardial ischemia, kidney injury, and ischemic stroke in the long term [12].

In these patients regardless of a number of organ dysfunction, the heat stroke survivors will have long-term functional and neurological disorders and impairment, with reported 28-day mortality of 58% and 2-year mortality of 71% [13].

### **13. Conclusion**

Heat stork is a severe temperature-related illness, an acute medical illness, and a medical emergency. It is more common in females than males. Heat stroke is defined as a core body temperature of more than 400 c with hot and dry skin associated with central nervous system dysfunction. Typically divided into exertional and non-exertional heat stroke. Heat stroke generates a systemic inflammatory and coagulopathy response in combination with heat injury causes organ dysfunctions. Diagnosed with raised body temperature with clinical manifestation and signs and symptoms of organ dysfunction or failure.

In the management of heat stroke ABCDE approach should be followed. Early body temperature management in combination with organ-supportive care will improve the clinical outcome. The mortality from heat stroke ranges from 58 to 71%. *Heat Illness and Critical Care*
