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## Meet the editor

Dr. Samy I. McFarlane is Distinguished Teaching Professor of Medicine/Endocrinology and Associate Dean at Downstate-Health Sciences University, Brooklyn, New York, USA. He has extensive experience in clinical and translational research and served as the principal investigator for the largest center in North America in the landmark Diabetes Reduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial. He

has authored more than 400 publications with more than 17,000 citations. Some of his citations are included in major guidelines by the American Heart Association (AHA), such as stroke guidelines (2018 and 2019), the Scientific Statement from the AHA on Lifestyle and Risk Factor Modification for Reduction of Atrial Fibrillation 2020, and the 2021 SHNE/HRS/EHRA/APHRS Expert Collaborative Statement. Most recently, Dr. McFarlane's work was cited by the WHO European Regional Obesity Report 2022. Dr. McFarlane is also the editor of several books on diabetes, hypertension, RAAS, dyslipidemia, cardiovascular disease, and related topics. He is the editor of the study guide, *First Aid for the Medicine Clerkship*, and the *Resident Inpatient Selective Educational (RISE) Manual* (2020 and 2022). Dr. McFarlane is the founding associate editor for *Endocrine Today* and a founding editor in chief, section editor, lead guest editor, and editorial board member for several journals, including *Clinical Practice*, *Current Diabetes Reports*, *Current Hypertension Reports*, *Current Cardiovascular Reports*, *International Journal of Hypertension*, and others. He is a three-term member of the National Institutes of Health-National Institute of Diabetes and Digestive and Kidney Diseases (NIH-NIDDK) and served twice as chair at NIH-NIDDK U01 committees. He also served as chair of the clinical sub-committee of the National Kidney Foundation, Kidney Early Evaluation Program (KEEP). Locally, he held several leadership positions including Director of Internal Medicine Clerkship, Program Director and Chief of Endocrinology, and Medical Director of Clinical Research. He is currently the Internal Medicine Residency Program Director at Downstate-Health Science University, Brooklyn, New York. He also served as Brooklyn District President for the American College of Physicians. Dr. McFarlane is the recipient of numerous awards and honors including recognitions from the United States Army, the US House of Representatives, and the Gold Foundation for Humanism in Medicine, in addition to several teaching and mentoring awards.

### Contents



Preface

While the pandemic of obesity continues to affect millions of people around the globe, major developments and insights into the pandemic and pathogenetic mechanisms of obesity-related disorders continue to evolve. Additionally, major developments in the management of obesity continue to progress with rather impressive outcomes.

In this volume, *Obesity – Recent Insights and Therapeutic Options*, we provide the latest developments in the field of obesity in a group of chapters written by experts in the field with direct and intricate knowledge of the disease through research and clinical

Section 1, "Implications of Obesity in Special Populations", includes Chapter 1, "Obesity in Children: Recent Insights and Therapeutic Options'' and Chapter 2, "Stigmatization of the Patients Who Live with Overweight or Obesity". The populations discussed in these chapters are particularly vulnerable and suffer from disparities and inequities in health care. However, they are finally gaining attention from

Section 2, "Metabolic and Neurogenic Effects of Obesity: Implications for Chronic Diseases," includes Chapter 3, "Metabolic Changes in Obesity", Chapter 4, "Diet-Induced Overweight Conditions: Effect on Brain Structure, Cognitive Function, and Neurogenesis" and Chapter 5, "Obesity: A Prerequisite for Major Chronic Illnesses".

This section provides current and practical information relevant to our understanding

This book is timely with useful and practical information that addresses the needs of a variety of readers, including students, busy clinical providers, and researchers alike.

Distinguished Teaching Professor of Medicine/Endocrinology and Associate Dean,

**Samy I. McFarlane**

United States of America

Downstate-Health Science University,

Finally, Section 3, "Recent Advances and Outcomes of Obesity Management", includes Chapter 6, "Novel Anti-Obesity Pharmacotherapies", Chapter 7, "The Role of Dietary Interventions in the Management of Obesity", and Chapter 8, "Metabolic Outcomes in Obese Patients after Bariatric Embolization of the Left Gastric Vessel". This section discusses recent advances in pharmacology and surgical interventions for obesity as well as presents information regarding the outcomes of these interventions.

health professionals, policy makers, and other stakeholders.

of the pathogenesis of obesity-related disorders.

practice.
