**Abstract**

Brain-computer interface is a technology that has been under enormous research in the last few decades. It uses brain signals by converting them into action to control the external environment. The focus of the future is the application of such technology in rehabilitating patients with physical disabilities. This chapter will mainly explore the use of EEG (electroencephalogram), a popular non-invasive method, on which the brain-computer interface is based. The process of signal extraction, selection and classification will be discussed. The challenges and techniques in communication and rehabilitation of people with motor impairment, along with the recent research study in this field, will be mentioned.

**Keywords:** brain-computer interface, electroencephalogram, neuro-rehabilitation, sensorimotor rhythm, evoked potential, motor imagery, hybrid, applications
