**5. Adherence of** *Candida albicans* **on PMMA mechanisms**

According to hydrophobic proteins on the surface of *Candida albicans*, this fungus is considered to be a highly hydrophobic substance. The adherence of *Candida albicans* to denture base surfaces has been associated closely with the hydrophobicity of the microorganism as a significant contributory physiochemical force.

For hydrophobic surfaces such as PMMA, monomer units exposed on the surface have interaction with the hydrophobic domains on a protein of *Candida albicans* by means of sturdy hydrophobic bonds. Therefore, the attractive hydrophobic interactions could bring about an inclination for *Candida albicans* to adhere greater with ease to hydrophobic surfaces than to hydrophilic surfaces. The contribution of electrostatic interplay between *Candida albicans* and polymeric surfaces is secondary to the hydrophobic force, due to the fact the adherence manner takes region in the presence of repulsive pressure [11].
