*1.2.3 Risk factors and individual Radiosensitivity*

The following risk factors predispose patients undergoing RT to develop severe ARD:


Risk factors for ARD can be considered determining factors for individual radiosensitivity. Radiosensitivity refers to the susceptibility to adverse effects resulting from exposure to ionizing radiation.

One of the challenges associated with planning the treatment of cancer patients is the identification of factors that influence the increase in individual radiosensitivity and decrease in tissue repair capacity [2, 3, 24]. However, patients with similar risk factors and treatment regimens may have different degrees of ARD. Furthermore, literature suggests that genetic factors can influence the tissue response to ionizing radiation [2].
