*1.2.2 Clinical management*

Several regular skin care guidelines, including cleaning the irradiated area daily using neutral soap and warm water without friction on the skin, drying gently, keeping the treatment area protected from sun exposure, and wearing looser clothes to avoid friction [13, 14, 16], are well documented in literature and patients should be oriented to these before beginning RT.

Although there are several skin care recommendations for the treated area before and during RT, these measures do not definitively prevent the development of ARD. However, it is still no consensus in the literature on the products that are effective in preventing ARD [7, 21, 22]. Therefore, the use of predictive mechanisms for the development of ARD would be a useful tool for improving treatment planning.
