*Long-Term Toxicities among Wilms Tumor Survivors DOI: http://dx.doi.org/10.5772/intechopen.110130*

The International Late Effects of Childhood Cancer Guideline Harmonization Group have recently published evidence-based consensus recommendations for fertility preservation, including testicular and ovarian cryopreservation, in young cancer patients [40]. Currently, fertility preservation for WT patients is largely experimental, expensive and not widely available. Most patients are prepubertal, and there are no established criteria and standard guidelines for fertility preservation in males and ovarian cryopreservation in prepubertal females. Clinicians should proactively initiate conversations around standard and experimental options for fertility preservation in high risk WT children. Other options that exist for WT survivors of both genders include adoption, surrogacy, and the use of donor sperm/ eggs or embryos.

The COG LTFU guidelines, version 5.0, provide extensive recommendations for the appropriate surveillance of childhood cancer survivors for common RT-induced toxicities observed in WT survivors (http://survivorshipguidelines.org). A summary of these guidelines is provided in **Table 3**.
