**Histopathological examination result:**

Invasive ductal carcinoma grade II

#### **Immunohistochemistry revealed:**

ER: positive PR: negative HER2: negative Ki-67: 50%

#### **4.3 Luminal B HER2 –ve breast cancer case presentation**

65-year-old female patient presented with right breast mass. Family history: Positive (**Figure 3**).

**Histopathological examination result:**

Invasive duct carcinoma grade II

#### **Immunohistochemistry revealed:**

ER: positive PR: negative HER2: negative Ki-67: 50%
