**2.7 Cutoff for TNBC**

In the 2011 St. Gallen recommendations, a cutoff of 14% for the separation of luminal A and B tumors is suggested [25]. In 2013, the cutoff was revised to 20%, signifying 20% as the cutoff level for differentiating low proliferating Luminal A from

#### *Breast Cancer Updates*

high proliferating Luminal B [26]. However, the best cutoff point of this marker as a prognostic and predictive factor in TNBC remains unclear.

