*4.5.2 Cardiac histoplasmosis*

Immediate procedural intervention is practiced when there is hemodynamic and respiratory decompensation due to pericardial or pleural damage. In severe cases, thoracocentesis or pericardiocentesis is performed in patients with large pleural effusions, respectively, cardiac tamponade [2].

If the pericardiocentesis is insufficient to alleviate the cardiac tamponade, it may be necessary to place the pericardial window.

Endovascular histoplasmosis can lead to valve infection and aneurysm formation, requiring surgical excision of the infected valves and aneurysm repair. In most cases, endovascular histoplasmosis cannot be cured with medical therapy alone.
