**Acknowledgements**

This work was supported by the Foundation for Science and Technology, I.P. (FCT), Portugal, through grant reference 2020.05884.BD, and by the Applied Molecular Biosciences Unit – UCIBIO, which receives financial support from Portuguese national funds (FCT/MCTES, Fundação para a Ciência e Tecnologia and Ministério da Ciência, Tecnologia e Ensino Superior) through grant UIDB/04378/2020.
