**3. Conclusion**

In this chapter the various work up for the synthesis of biologically potent Thiazolidinone derifvatives are discussed and the wide spectrum biological activities are elaborated. The clinically utilised medications no longer have any of the 4 thiazolidinone nucleus' efficacy. Although the four main clinical uses of title compounds are antibacterial, antitubercular, antiviral, and antidiabetic, other potential targets need to be investigated. The majority of locations were investigated to enhance the 4-thiazolidinone's antibacterial and antitubercular profile, however none of the derivatives shown encouraging antitubercular activity. However, few derivatives of 4 thiazolinone with C-2 and N-3 substituted positions and the presence of electronwithdrawing substituent on the aromatic ring at C-2 position exibit varying degrees pharmacological activity. The clinically utilised medications no longer have any of the 4-thiazolidinone nucleus' efficacy.

*Synthesis and Biological Applications of Thiazolidinone DOI: http://dx.doi.org/10.5772/intechopen.109102*
