**9. Conclusion**

Drugs like Nucleoside reverse transcriptase inhibitors, Non nucleoside reverse transcriptase inhibitors, Protease inhibitors, Integrase inhibitors and Fusion or Entry inhibitors are the potent candidates as anti HIV and efforts are still continuing to develop potent molecules which will be effective in the management of AIDS, and search is still going on as viruses exhibited rapid mutation which makes the drug ineffective against the treatment of AIDS and develop resistance against multiple drug therapy and drug become active only for short span of life.

As most of anti HIV agents have diverse chemical structures showed in this book chapter which exhibited potent action against many viruses and considered as best candidate as anti HIV.

The current Covid-19 problem is an excellent example of mutant variation of viruses which exhibited variant strain rapidly and for the reason of developing resistance against many anti-viral drugs. Combination of NRTI and NNRTI along with PI are used administered to combat with drug resistance and be a part of multi drug resistance therapy.
