**2.5 Cu(II), Ni(II) and Zn(II) complexes**

2-Methoxybenzaldehyde-S-2-methylbenzyl dithiocarbamate and 3-methoxybenzalde hyde-S-2-methylbenzyl dithiocarbamate and its Cu(II), Ni(II), Zn(II) complexes were inactive against MCF-7 and MDA-MB-231 breast cancer cell lines [64].

**Figure 4.** *Cytotoxic activity of Cu(II), Zn(II) and Ni(II) complexes of thiosemicarbazones.*
