**4.5 Novel drug delivery**

Captivatingly, CD and its derivatives have been employed to develop the novel systems having supramolecular architectures such as micelles [48], nanosponges [49], nanoparticles [50], nanovesicles [51], etc., to build the functional platforms. Among these delivery systems, lipid nanocarriers are arguably the most common nanomaterials, which are used in association with modified CDs. Being biodegradable and

*Cyclodextrins: An Overview of Fundamentals, Types, and Applications DOI: http://dx.doi.org/10.5772/intechopen.108078*

biocompatible, these systems offer versatile advantages including targeted delivery, stability, and co-drug loading (i.e., both hydrophobic and hydrophilic). In addition, they also exhibit superior efficacy and pharmacokinetics [52]. Conducive studies on the lipid nanosystems including parent and derivated CDs have proven the suitability of this approach to enhance the bioavailability of numerous pharmaceutical formulations; hence, continually increasing its implications in different disorder, for instance, diabetes [53], hypertension [54], cancer [55], and many other ailments.
