**5.2 Growth factors**

Platelet-derived growth factor, a mitogenic bioactive molecule, encourages undifferentiated mesenchymal cells to develop into mature tissue, which increases the production of new cells and speeds up wound healing. Additionally, platelets have the ability to promote angiogenesis and tissue migration from a preformed vascular bed. They can also provide vascular endothelial synthesis a final boost by inducing vasodilation [31].
