**8. Conclusion**

Diabetic foot ulcers have protocols for treatment and prevention but ultimately the only way to prevent them entirely is to address the diabetes of the patients involved. Although this review is not entirely a comprehensive review of diabetes, it is clear that its prevention is not a simple matter especially if its cause and treatment are not necessarily well defined. Since there are two prevailing theories of its cause and there are different types of diabetes and diets the effects of microbiota and diet are not going to be the same for everyone. **Figure 1** is a simplified diagram of all the players. Microbiota and Diet have a great influence on incretin action and glycemic control but SCFA, incretins, and insulin all have direct effects on the deposition of fat in adipocytes. Not listed in **Figure 1** is that glucose itself can be synthesized into fats. Incretins can affect glucsose metabolism by turning glucose into fats especially when the insulin levels are high.
