**3.4 Infection treatment**

Antibiotic treatment for DFU will be administered based on the pathogen that is most likely causing the infection and the severity of the illness. It can be tweaked based on the findings of the microbiological culture and the treatment's effectiveness. The duration of antibiotic treatment is determined by the severity of the illness; for example, a moderate infection might be treated for 1–2 weeks, a severe infection for 2–4 weeks and osteomyelitis for longer [29]. Dicloxacillin, cephalexin, clindamycin and amoxicillin/clavulanate are recommended antibiotics for mild-moderate cases; vancomycin + ampicillin/sulbactam, moxifloxacin, cefoxitin or cefotetan for moderate cases; and vancomycin + piperacillin/tazobactam, imipenem/cilastatin, meropenem or doripenem for severe cases [29, 30, 31].
