*Perspective Chapter: Immunosuppression in Patients with Diabetes Mellitus DOI: http://dx.doi.org/10.5772/intechopen.107362*

that aggravate the inflammatory state and lead to hyperglycemia as a result of the inhibition of insulin signalling. Both issues with the innate immune response (including neutrophil and macrophage dysfunction) and deficiencies in the adaptive immune response are thought to contribute to the immune system's degradation against invasive infections in diabetics (including T cells). A deeper understanding of the processes of hyperglycemia that impair host defence against pathogens is crucial for the development of cutting-edge treatments to treat infections in diabetic patients and improve treatment outcomes.
