**7. Summary**

The mucosal system is the body's first line of defence against infection and SIgA is the primary immunological weapon. Although there have been significant advancements in the understanding of this antibody complex, SIgA has been overshadowed by the therapeutic success of IgG antibodies. Renewed interest in mucosal vaccines and oral immunotherapy has highlighted that existing therapeutics may not be best suited for mucosal therapy, ushering a potential new era of SIgA-based therapy. This chapter has highlighted that:

