**1. Introduction**

Chronic Obstructive Pulmonary Disease (COPD) afflicts more than 390 million people globally [1] and is the third leading cause of death worldwide [2]. COPD is also a heterogeneous and complex malady, varying in severity and clinical presentation. The commonness and the complexity of this disorder require contextualization in balancing global scientific development with the local milieu, and the general aspects of the disease with particular subject characteristics.
