**7. Summary**

The current standard of treatment for acute ischemic stroke is thrombolysis. However, only 2−8.5% of stroke patients can undergo thrombolysis in America, and less than 2% in the world undergo thrombolysis.

Green tea (*C. sinensis*) is the most consumed beverage in the world and is a source of polyphenols known as catechins, including epigallocatechin-3-gallate (EGCG), which is 63% of total catechins.

*C. sinensis* with the active ingredient EGCG inhibits neuronal cell death through apoptosis (increased expression of BCL-2 and decreased expression of Caspase-3) and necroptosis (decreased expression of TNFR1 and RIP 3) in acute ischemic stroke as in the R. norvegicus model of Middle Cerebral Artery Occlusion (MCAO), it also can decrease necroptossis and increase M2 type microglia.

*Green Tea with Its Active Compound EGCG for Acute Ischemic Stroke Treatment DOI: http://dx.doi.org/10.5772/intechopen.107068*
