**2. History and discovery of curcumin**

Curcumin can be obtained from C. longa rhizomes, a plant of Zingiberaceae, and it is the main functional compound in turmeric. Curcumin was initially found around 200 years ago when Vogel and Peltier extracted a "yellow substance" from C. longa Linn's rhizomes and termed it curcumin. Milobedeska et al. [5] described it, and Lampe [6], made it for the first time.
