**5. Conclusion**

The safety profile of curcumin is exceptional, and it has multiple health benefits including anti-inflammatory, antioxidant, antitumor, antibacterial, and anti-diabetic properties. However, the poor stability in the body fluids, rapid clearance, and low aqueous solubility limit curcumin's clinical use. Nano-based drug delivery systems are currently opening a new world of possibilities for solving these problems. Nanoparticles have been shown to improve the solubility and stability of some substances including curcumin and amend its curative index. Therefore, targeting curcumin-loaded nanoparticles for therapeutic purpose is a promising strategy.
