**5. Summary**

Boron neutron capture therapy (BNCT) is a type of radiotherapy, but it has cell selectivity and can be used in combination with other radiotherapy for the treatment of recurrent and irradiated cases. The major adverse events are radiation-induced necrosis and brain edema especially for the patients with history of prior irradiation in the central nervous system.

BNCT using borofalan (10B) has become a general medical treatment by the development of medical equipment using the accelerator as a neutron source.
