**Abstract**

One of the most futuristic and unique carbon materials which is formed from detonation method is nanodiamond. Nanodiamonds below 100 nm size popularly known as attracting crystal or ultrafine dispersed diamonds (UDD) have exceptional optical, mechanical, and biological properties. The structure of nanodiamonds resembles diamond structure. Due to the peerless properties, Nanodiamonds make itself potential to several applications. Nanodiamonds became demand in medical field. Currently, Nanodiamonds acquired substantial recognition in all areas particularly nanomedicine. This chapter opens a detailed review about the evolution of Nanodiamonds, their properties, applications and future perspectives in research. Researchers are still doing their studies on nanodiamonds to make an effective tool in various sectors.

**Keywords:** Nanodiamonds, structure, synthesis, properties, laser ablation
