**4. Conclusions**

The voltage-gated sodium channel Nav1.7 has been shown to play an important role in human pain signaling through neuronal excitability. Studies of different rare conditions point to the SCN9A gene, which codes for said channel as the one responsible for its gain or loss of function, which has demonstrated its intrinsic relationship with pain, this has given rise to the Nav channel 1.7 is an interesting therapeutic target to develop analgesics, despite the fact that a large catalog of channel antagonists have been discovered, there is still no certainty for their medical prescription, however, there is extensive and promising research in clinical trials to exploit the characteristics of Nav1.7 and there are, in the future, specific drugs that relieve patients of severe pain, thus improving their quality of life.
