**Abstract**

The lignin biodegradation initiate mainly by the fungi organisms and particular interest is focus on the white-rot fungi because apart to use cellulose as carbon source and energy, also can degrade lignin by ligninolytic enzymes such as lignin peroxidase (LiP), manganese peroxidase (MnP), laccases (Lac), and versatile peroxidase (VP). Interesting results, are reported that these enzymes are involve in the degradation of some persistent organic pollutants such as organochlorines. The mechanism to degrade the organochlorines, is thanks apparently by laccase enzymes and other mono and dioxygenases like MnP and VP which can transform chlorophenols to innocuous by-products facilitating the uptake by the fungus or other microorganisms. The use of these different fungus or their enzymes can help to reduce the pollution on the environment (water and soil systems) reducing the negative effects on aquatic animals, plants, and animals including the human being.

**Keywords:** lignin, biodegradation, laccase, enzymes, fungi
