**2. Why science takes a fundamental role in neuroplasticity?**

Understanding part of the physiology of the nervous system has been one of the most outstanding achievements of the 20th century. It is indisputable that these achievements could not have happened if there was no research involved, so as the interest of the scientific community to try to explain the mechanisms of the brain. The decade from 1990 to 2000 was established by the American Academy of Neurology (AAN) as the "decade of the brain" [1], and it was a transition between elemental bases of neuroscience to a more specific so-called era. It is important to mention that in the 21st century, the growing curiosity to investigate and explain neurophysiology has reached unprecedented milestones due to emerging technologies that have been crucial for research and clinical practice. Topics such as memory, neuroplasticity, neurobiochemistry, neuronal tracts, sprouting, and neuroimmunology are reaching new horizons because of the molecular approach [2]. This is the reason why it should be investigated the neuroplasticity and forgetting. Not just as a new trend, but rather as fields of neuroscience that must be discussed by the community in order to achieve progress. Without the new biotechnology, and in this case neurobiotechnology; discovering and knowing the molecular mechanisms of plasticity, memory, and forgetting would be impossible.
