**8. Conclusions**

Forgetting or forgetfulness is a neurologic active state in which the subject or the patient has an impossibility to obtain old information stored in their memory. Neuroplasticity is a fundamental concept when approaching forgetfulness. Macroscopically, the neuronal circuitry is not damaged, although its molecular scene changes the opportunity to retrieve the information. It is important to mention the existence of drugs that improve amnesia (which is not the same as forgetting), and it is possible to act over forgetfulness. There are no medications to help forget, in cases of sleepiness, mental trauma, or aging. The use of DBS or TMS could be a possibility to increase or decrease, in other words, neuromodulate forgetting.
