**2.4 Other environmental factors**

Other environmental factors that could contribute to the development of CD have also been studied, such as the time and manner of introduction of gluten, the type of delivery, the start and duration of breastfeeding, the microbiome or early exposure to antibiotics, among others [29, 30]. However, the studies carried out to date do not confirm the different hypotheses proposed. Recently, the link between viral infections and loss of oral gluten tolerance has been investigated, since infections caused by rotavirus, reovirus, astrovirus, enterovirus, and adenovirus are very common in childhood. This opens the door to a new field of knowledge that could allow the design of preventive strategies in the future of CD [31, 32].
