*5.2.2 Pulse wave velocity: PWV*

Noninvasive evaluations of vascular elasticity have also been well documented. Pulse-wave velocity (PWV) is a representative parameter for evaluating arterial stiffness. PWV is a simple and noninvasive test for evaluating arterial stiffness. PWV can be measured from various arterial sites, and pressure waveforms are usually obtained percutaneously at the common carotid and femoral arteries. Several methods have been developed to measure PWV, including aortic PWV, brachial-radial PWV, and brachial-ankle PWV. There have been some reports on the measurement of brachialradial or brachial-ankle PWV, showing a significant increase in arterial stiffness in the KD group compared with the control group, regardless of whether the patients had

CAL [33–35], however, the relationship between vascular stiffness and prognosis is not clear. Although aortic PWV is a known predictor of cardiovascular events [36], no large prognostic studies examining the association between brachial-radial or brachial-ankle PWV and cardiovascular events have been performed. This limitation should be noted when the PWV is used.
