**Abstract**

As one of the novel interesting fields of cardiology, cardio-oncology focuses on monitoring, detecting, and treating cardiovascular diseases caused due to chemotherapy or radiotherapy side effects. It has been observed that cardiovascular patients have a higher risk of viral infections and poorer treatment outcomes. COVID-19 is a disease caused by the new coronavirus, SARS-CoV-2, which emerged in Wuhan, China, in 2019 and then distributed worldwide. Recent evidence showed that the risk of COVID-19 and its mortality rate is higher in patients suffering from cardiovascular side effects of cancer therapies. Additional diagnosis complexity in cardio-oncology is another problem due to overlapping with COVID-19. Therefore, the cardio-oncology community had to re-evaluate the best clinical care in the COVID-19 pandemic. The present study aims to review previous studies focusing on the interaction between COVID-19 and cardio-oncology, which will pave the way for studying human diseases overlapping with COVID-19.

**Keywords:** cardio-oncology, COVID-19, cancer, cardiovascular, SARS-CoV-2, signaling pathway
