*3.1.4.9 Cognitive dysfunction*

Cognitive deficit is extremely common in lupus cases, varying within the range of 20–80% [32, 33]. It may, however, not be reasonable to attribute deficit in cognition to the activity of the disorder, SLE burden, and corticosteroid treatment [32].

## *3.1.4.10 Psychosis*

Organic psychosis may influence 2 to 11 percent of SLE cases. In about 60% of such cases, it emerges as the SLE-symptom [34]. SLE psychosis is often associated with SLE activity and is affected by immunosuppressive treatments. One important differential diagnosis is corticosteroid-activated psychosis. However, it is not more prevalent in SLE in comparison with the rest of autoimmune conditions [35]. Studies have also detected a positive linkage between SLE and the danger of being affected by schizophrenia [36, 37].
