**4. Differential diagnosis of VLU**

The success of the treatment of venous ulcers of the lower extremities depends on the accuracy of the diagnosis. Infectious ulcers are mostly found in the tropics, while neoplastic ones are relatively rare. Ulcers associated with rheumatic disease or diabetes are also common in everyday clinical practice [7]. There is a whole range of etiological causes of ulcers on the lower extremities (**Table 1**).


**Table 1.**

*Differential diagnosis of leg ulcers.*
