**8. Conclusion**

Venous leg ulcers occur as a complication of CVI. Venous leg ulcers are significantly more common in the elderly. A VLUs represent a growing health problem, and they are a condition that is very expensive to treat for both the health system and patients. The application of modern diagnostic and therapeutic modalities in the treatment of VLUs in combination with available evidence-based data will reduce the number of patients who will not heal and who will relapse. Therefore, the use of standard treatment methods and the use of expensive advanced therapeutic agents is of particular importance.
