**5. Principles of VLUs treatment**

The therapy of VLUs is complex and is determined on the basis of: etiology, clinical picture, echosonographic findings, thrombotic status, laboratory findings, comorbidities, nutritional deficiencies, risk factors, economic and medical possibilities for diagnosis and therapy. The goal of therapy is complete restitution (reconstruction) of the tissue defect and prevention of recurrence [25]. Improvement of hemodynamic status (reduction of venous hypertension and venous stasis) is the primary therapeutic goal. The three basic elements of VLUs therapy are [26]:

*Perspective Chapter: Diagnosis and Treatment of Venous Leg Ulcer DOI: http://dx.doi.org/10.5772/intechopen.105676*


Adequate VLUs therapy should reduce venous hypertension in the micro and macro circulation [26].
