*Nanotechnological Interventions and Mechanistic Insights into Wound-Healing Events DOI: http://dx.doi.org/10.5772/intechopen.106481*

physicochemical properties and their possible toxicity remains a huge hurdle in promoting these nanotechnologies for human use. Recent developments in the nano-field have led to the development of matrices, scaffolds, skin substitutes, embedded/loaded dressings, etc., which mimic the integrity of the skin. Soon unique phenotype–genotype characteristics will lead way to tailored therapies. This will provide a platform to create new nanotechnology-driven approaches, hence, streamlining and facilitating personalized treatment plans.

For the clinical translation of nanotechnology-based products, there is an urgent need for improved tools and better analytical methods. Comprehensive efforts are necessary to develop chronic wound care products with target and site-specificity to negate the undesirable effects of the nanosystems in humans. In due course of time and with the ever-increasing reports about exciting new nanotechnology platforms, the day is not far when the international standards on biocompatibility and toxicity of various nanotherapies are met with. In a nutshell, our current knowledge about the development of nanotherapeutics, together with our understanding of phenotype– genotype characteristics and chronic wound pathology, will be instrumental in promoting and conceptualizing next-generation wound repair nanotechnologies.
