**3. Conclusion**

In conclusion, biomarkers were indicators of normal physiological processes, disease progression and response to treatment. Although many biomarkers for asthma have been mentioned in recent studies for the diagnosis of asthma, the identification of different phenotypes and efficacy evaluation, none of them have been approved for clinical practice so far, mainly due to their limited sensitivity and specificity. With the development of biomedicine, asthma research is moving from clinical symptoms, clinical phenotypes, lung function and medication response to genomics, proteomics, epigenetics, etc. More key molecules and biomarkers will be discovered in the future. Combined detection of multiple markers can more comprehensively analyze the patient's condition, thus providing more valuable clinical information for the diagnosis, classification and treatment of asthma, and ultimately achieving accurate diagnosis and treatment of asthma patients.
