**2.2 Sources of information**

The data search was carried out using three electronic databases: PubMed, ScienceDirect, and Trip database. Data collection was conducted from January to December 2021. Studies identified in the references of the selected articles, and that met the inclusion criteria were included in this review (**Figure 1**).

### **2.3 Search strategies**

The keywords used were: asthma, child, adolescent, caregivers, quality of life, education, and disease management.

These terms were combined via the Boolean switch statement "AND" and "OR", as following: (("Asthma"[Mesh]) AND "Child"[Mesh]) AND "Quality of Life"[Mesh]; ((("Asthma"[Mesh]) AND "Disease Management"[Mesh])

*Effect of Family Education on Clinical Outcomes in Children with Asthma: A Review DOI: http://dx.doi.org/10.5772/intechopen.105205*

#### **Figure 1.**

*The studies' selection procedure. a RCT: Randomized controlled trials.*

AND "Child"[Mesh]) AND "Caregivers"[Mesh]; (((("Asthma"[Mesh]) AND "Child"[Mesh]) AND "Adolescent"[Mesh]) AND "Education" [Subheading]; (((("Asthma/nursing"[Majr] OR "Asthma/rehabilitation"[Majr] OR "Asthma/ therapy"[Majr])) AND ("Patient Education as Topic/education"[Majr] OR "Patient Education as Topic/methods"[Majr] OR "Patient Education as Topic/organization and administration"[Majr])) AND "Family"[Mesh] AND "Child"[Mesh].

Randomized controlled trials and quasi-experimental studies published in English from 2010 to December 2021 were considered.

#### **2.4 Selection criteria of the studies**

Studies were primarily selected based on the titles and abstracts. After the exclusion of duplicates, studies were assessed according to the established inclusion criteria. Included studies were quasi-experimental studies or randomized controlled trials conducted in children with asthma aged between 6 and 18 years and their parents, and published (or accepted for publication) in English from January 2010 to December 2021. Abstracts and research protocols were excluded.

#### **2.5 Data extraction**

For each study included in this literature review, the following variables were identified: country and year of publication, study design, study groups, follow-up assessment, intervention approach, intervention duration, number of sessions, duration of each session, theoretical framework (if applicable), and clinical outcomes and their measurement tools.
