*3.15.6 MPC inhibitors*

The mitochondrial pyruvate carrier (MPC), a combination of two proteins, is crucial for the lipogenesis process in which carbohydrates are converted to fatty acids. Clinical investigations have shown that MPC inhibitors increase insulin sensitivity, reduce liver steatosis, and lower liver enzyme levels.

**Figure 13.** *Gut microbiota and its role in NAFLD/NASH.*
