Preface

Animal models and experimental research in medicine involve the use of animals to learn more about diseases and treatments in humans. Animal models are used to understand physiological, biochemical, and pathological mechanisms of cells, tissues, organs, and systems to elucidate inter-system relations and develop new diagnostic methods for diseases or functional disorders as well as new strategies for their treatment. Research may involve testing the effects of new drugs on animal models or studying the effects of environmental factors on the progression of diseases. Animal models are also used to gain insights into the behavior of disease processes and to develop new diagnostic tools and treatments. Evaluation of some biomarkers and even researching and finding new biomarkers to diagnose prognosis and treatment of diseases that are seen frequently will both help in the treatment of diseases and shorten this process considerably.

*Animal Models and Experimental Research in Medicine* contains chapters authored by international researchers that address experimental models of amyotrophic lateral sclerosis, hepatotoxicity, liver fibrosis/cirrhosis, visceral hyperalgesia, and female reproduction, as well as some fish studies and cardiovascular research in large animal models. Overall, this book offers essential information that will be helpful to researchers and scientists in medicine, biology, veterinary medicine, and other related fields who are interested in learning more about animal models and experimental research in medicine as well as ideas that will contribute to future research. It is a useful resource for medical professionals, students, and educators who are looking to better understand how animal models can be used to study and treat diseases.

#### **Mahmut Karapehlivan**

Faculty of Medicine, Department of Biochemistry, Kafkas University, Kars, Turkey

#### **Abdulsamed Kükürt**

Faculty of Veterinary Medicine, Department of Biochemistry, Kafkas University, Kars, Turkey

#### **Volkan Gelen**

Faculty of Veterinary Medicine, Department of Physiology, Kafkas University, Kars, Turkey

**1**

Section 1

Animal Models in Various

Diseases
