**Figure 26.**

*CSII start: suggested distribution of basal rates over 24 h; to be individually adopted according to glycaemic profiles and clinical experience.*


Insulin pumps are the optimum available and safe means for insulin substitution in PWD1 [117, 118]. From insulin pumps may also profit some PWD 2 [106, 119].

*Intensive Management of Type 1 Diabetes in Adults: One Centre Experience 1970–2022 DOI: http://dx.doi.org/10.5772/intechopen.108032*

## **Figure 27.**

*Distribution of PWD (PARASEN Group) with accepted or rejected insulin pump or switched to other treatments or decreased over the period of 31 y.*

**Figure 28.**

*Summary of outcomes from insulin pump treatment of PWD (PARASEN Group) over the 31-year period 1981– 2012.*

However, in PWD2 incretins and gliflozins recently appear to offer better cardioprotective and nephroprotective perspectives.
