**Figure 18.**

*George's absolute values of HbA1c, BM, and INS/d over 19 months illustrate the initial rapid correction of HbA1c (from 120 to 51 mmol/mol) after initiation of insulin treatment by insulin pen. Later, there is sufficient HbA1c control, at the expense of the high insulin delivery, up to 50 IU/d (red box), and thus an increase in body mass (from 94 to 104 kg). HbA1c concentration was not measured on August 29, 2022.*
