**3.4 Secretion and other soluble markers of activation**

Urinary excretion of thromboxane B2 (TXB2) was found higher in DM than in healthy controls [35]. This is in contrast to another study that found decreased levels of TXB2, β-Thromboglobulin (BTG) and platelet factor-4 (PF-4) in diabetic patients with uncontrolled blood sugar and high HbA1C [34].
