**2.3 Platelet morphology and ultrastructure in T1DM**

Peripheral blood smears of patients with diabetic complications show occasional giant platelets [8]. Biochemical examination has revealed altered membrane lipid composition, as well as Na +-K+ ATPase and Ca++-ATPase, which are sensitive to glucose concentrations compared with control from non-diabetic subjects [18].

Ultra structural examinations show prominence of dense granules.
