**2. Conclusion**

Melatonin hormone is a critical component in treating sleep and other body disorders arising from the disruption of the circadian rhythm. Melatonin comes as an endogenous or exogenous hormone, where endogenous derives naturally from the body and exogenous is manufactured in the laboratory. With respect to endogenous melatonin, it derives from the pineal glands in the brain and undergoes various processes before attaining its ultimate outcomes. Particularly, melatonin undergoes biosynthesis and catabolism, and the metabolites are distributed throughout the body to different types of receptors. Melatonin concentration measurement thus becomes possible by testing the end products from different sites using gauging models, such as RIA and ELISA. The essence of understanding melatonin demographics is mainly to connect its connection with the circadian rhythm in facilitating body cycles. Precisely, the melatonin hormone undergoes its processes in resonance with the circadian rhythm for it to complete its physiological pathways. Therefore, exploring

#### *Melatonin - Recent Updates*

the connection between melatonin production and circadian rhythms helps understand the body's physiological processes in contracting or treating sleep disorders. Conclusively, every non-photic factor has been found to have a significant effect on endogenous melatonin. Several studies have exhausted the effects including increase or decrease of melatonin levels upon experiments on the different non-photic factors.
