**5. Conclusion**

In this chapter, we described how inflammation triggered by virus infection can lead to ocular complications capable of progressing to degenerative diseases such as AMD.

In particular, ocular complications due to COVID-19 and Zika virus have been analyzed, unfortunately this area of research is not yet well explored; especially in the former case given the recent appearance of the new virus responsible for Sars-Cov2 that is constantly evolving.

As for Zika virus, although the etiology at the level of the central nervous system and at the ocular level is known, effective therapies capable of blocking viral replication are not yet available; in fact, a specific vaccine is not yet developed.

Studies on the anti-inflammatory ability, at the ocular level and on retinal degeneration, of natural molecules have been widely resonant in the last decade; this strategy has also received interest in the treatment of Zika-virus-induced inflammation, and promising studies indicate the ability of molecules such as resveratrol and hesperetin to block the viral cell cycle. These notions, while in need of further study, open new perspectives for phytonutrient treatment of virus-induced ocular complications.
