*Genetic Targets May Be a Promising Future for Osteoporosis DOI: http://dx.doi.org/10.5772/intechopen.110336*

association which it is caused by this SNP. The genotypes of the LRP5rs121908669 were distributed according to three groups (GG, CC, and GC).

Several statistical applications (binary logistic regression test, Related-Samples McNemar Change Test, chi-square test) were used to study the relationship between mild osteogenesis imperfecta and postmenopausal osteoporosis and osteopenia. Chisquare test was used to study the association between carrier of (mild osteogenesis imperfecta—postmenopausal osteoporosis, osteopenia) and clinical data (height, age of onset of bone complaint). Statistical applications (Related-Samples McNemar Change Test, chi-square Test, Odd Ratio test) were used to study the relationship of genotypes of LRP5rs121908669 with femur T-score and the relationship of genotypes of LRP5rs121908669 with lumbar T-score. Chi-square test, Odd Ratio test, and likelihood ratio test were used to study the relationship of genotypes of LRP5rs121908669 with clinical data (body mass index).
