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## Meet the editors

Prof. Dr. Karl Fredrik Almqvist trained at the University of Ghent, Belgium, and worked at the Ghent University Hospital where he was head of the clinic, Department of Physical Medicine and Orthopaedic Surgery before moving to Dubai in 2014. He has published extensively and written several book chapters. He is a regular speaker at international meetings and is an editorial board and reviewer for the major sports orthopaedics jour-

nals. He obtained his Ph.D. in 2001 with his study, "Human differentiated articular cartilage cells in biodegradable matrices – Preparative studies for their use in the repair of cartilage defects." Dr. Almqvist is active in several orthopaedic organizations and is the past chairman of the Sports Committee of the International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine as well as the past chairman of the Cartilage Committee of the European Society of Sports Traumatology, Knee Surgery and Arthroscopy, and ISAKOS Board Director member. His main area of interest is knee surgery. His expertise covers the whole range of knee conditions from sports injuries to knee replacement.

Assistant Prof. Dr. Taiceer Abdulwahab is an orthopaedic surgeon at Mediclinic City Hospital, Dubai, UAE, and Assistant Clinical Professor of Orthopaedic Surgery at the Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), Dubai, UAE. He obtained a ChM in Trauma and Orthopaedic Surgery from the University of Edinburgh School of Medicine in partnership with the Royal College of Surgeons

of Edinburgh, UK. He received an MSc in Trauma and Orthopaedic Surgery from Warwick School of Medicine, University of Warwick, UK, where he also obtained a postgraduate award (PGA) in Understanding Research and Critical Appraisal. Dr. Abdulwahab obtained his MBChB from the Bristol School of Medicine, University of Bristol, UK. He is a member of the Royal College of Surgeons of England (MRCS). He has presented at various international conferences including the International Congress for Joint Arthroplasty (ICJR) and the European College of Sports and Exercise Physicians (ECOSEP) with FIFA update. He has published papers in peer-reviewed journals and edited one book. He is also an investigator in several randomized controlled trials. He is the trauma doctor for the annual Emirates Rugby 7s. He has a special interest in sports surgery (arthroscopic shoulder and knee surgery). Outside of his work, Dr. Abdulwahab enjoys reading and is an active cyclist, competing in an annual 100-km race.

Dr. Ahmed Elhamaky is a qualified orthopedic specialist in trauma and sports medicine, currently practicing at Mediclinic City Hospital, Dubai, UAE. With a deep passion for his field, Dr. Elhamaky has dedicated his career to providing exceptional patient care and advancing the field of orthopedics. Dr. Elhamaky's journey began with his pursuit of higher education at Cairo University, Egypt, where he obtained his master's

degree in Orthopedic Trauma and Disease. During his time at Cairo University, he

received comprehensive training in various aspects of orthopedics, honing his skills and knowledge under the guidance of experienced professionals. Driven by a thirst for knowledge and a commitment to excellence, Dr. Elhamaky further expanded his expertise through specialized training at prestigious institutions. He completed training programs at Cairo University's Orthopedic Department, Elhelal Hospital, and the Military Air Force Hospital in Egypt. These experiences allowed him to gain extensive experience in orthopedic trauma and equip him with the necessary skills to handle complex cases. In his pursuit of excellence, Dr. Elhamaky focused on advancing his expertise in hip and knee joint arthroplasty, as well as knee arthroscopic sports injuries. This specialized training enabled him to offer advanced surgical interventions and provide optimal care for patients with joint-related issues and sports-related injuries. Additionally, Dr. Elhamaky holds the esteemed position of adjunct clinical assistant professor at the Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), Dubai, UAE. This role allows him to contribute to the education of future doctors.

### Contents


Preface

This book presents the latest research and treatment options in cartilage disorders. It provides an in-depth understanding of the cutting-edge research, technologies, and

Over the past few decades, there have been significant advances in our understanding of the pathophysiology of cartilage disorders as well as in the development of new treatment options for these conditions. Cartilage disorders are complex and multifactorial, and they can cause significant pain and disability in affected individuals. It is therefore essential to have a thorough understanding of the latest research and

Written by leading experts in cartilage research, the chapters in this textbook provide an in-depth analysis of the latest research findings and treatment options. The book is divided into two sections. Section I provides an overview of the basic science of cartilage biology, including the structure and function of cartilage, as well as the molecular mechanisms that underlie cartilage disorders. Section II focuses on the clinical aspects of cartilage disorders, including the regenerative techniques and treatment of these

The chapters in Section I cover topics such as the structure and composition of cartilage, the molecular mechanisms of cartilage degeneration, and the role of inflammation in cartilage disorders. The authors also discuss the latest advances in imaging and biomarker technologies, which have greatly enhanced our ability to diagnose

Section II of the book focuses on the clinical aspects of cartilage disorders, including the evaluation and management of patients with cartilage injuries. The authors provide detailed descriptions of the various techniques used to repair and regenerate damaged cartilage, as well as the latest advances in cell-based therapies and tissue engineering approaches. The association of cartilage lesions and ACL injuries is also highlighted in

The editors of this textbook have taken great care to ensure that the content is both informative and accessible to specialized orthopedic surgeons. The chapters are written in a clear and concise style, and they are accompanied by numerous illustrations and diagrams to aid in understanding. In addition, each chapter includes a comprehensive

In conclusion, this textbook represents a comprehensive and up-to-date resource for specialists who are interested in the latest research and treatment options in cartilage disorders. We hope that readers will find this book to be a valuable addition to their professional library and that it will enhance their ability to provide the best possible

reference list to facilitate further reading and research.

treatment options currently available to orthopedic surgeons.

treatment options to provide the best possible care to patients.

conditions.

depth.

care to their patients.

and monitor cartilage disorders.
