**7. References**


Burdett, S., Stewart, L.A., & Rydzewska, L. (2007). Chemotherapy and surgery versus surgery alone in non-small cell lung cancer. *Cochrane database of systematic reviews,*  Vol.18, No.3, (July 2007), CD 006157

Neoadjuvant Chemotherapy in Malignant Pleural Mesothelioma 117

Malignant Pleural Mesothelioma: A Phase II Trial. *Journal of Thoracic Oncology.* Vol. 1,

Flores, R.M., Pass, H.I., Seshan, V.E., Dycoco, J., Zakowski, M., Carbone, M., Bains, M.S., & Rusch, V.W. (2008). Extrapleural pneumonectomy versus pleurectomy/decortication in the surgical management of malignant pleural mesothelioma: results in 663 patients. *Journal of Thoracic and Cardiovascular Surgery,* Vol. 135, No. 3, (March 2008), pp.

Kalmadi, S.R., Rankin, C., Kraut, M.J., Jacobs, A.D., Petrylak, D.P., Adelstein, D.J., Keohan, M.L., Taub, R.N., & Borden, E.C. (2008). Gemcitabine and cisplatin in unresectable malignant mesothelioma of the pleura: a phase II study of the Southwest Oncology

Krug, L.M., Pass, H.I., Rusch, V.W., Kindler, H.L., Sugarbaker, D.J., Rosenzweig, K.E., Flores, R., Friedberg, J.S., Pisters, K., Monberg, M., Obasaju, C.K., & Vogelzang, N.J. (2009). Multicenter Phase II Trial of Neoadjuvant Pemetrexed Plus Cisplatin Followed by Extrapleural Pneumonectomy and Radiation for Malignant Pleural Mesothelioma.

Manegold, C., Symanowski, J., Gatzemeier, U., Reck, M., von Pawel, J., Kortsik, C., Nackaerts, K., Lianes, P., & Vogelzang, N.J. (2005). Second-line (post-study) chemotherapy received by patients treated in the phase III trial of pemetrexed plus cisplatin versus cisplatin alone in malignant pleural mesothelioma. *Annals of Oncology,* 

Marinaccio, A., Binazzi, A., Cauzillo, G., Cavone, D., Zotti, R.D., Ferrante, P., Gennaro, V., Gorini, G., Menegozzo, M., Mensi, C., Merler, E., Mirabelli, D., Montanaro, F., Musti, M., Pannelli, F., Romanelli, A., Scarselli, A., & Tumino, R. (2007). Analysis of latency time and its determinants in asbestos related malignant mesothelioma cases of the Italian register. *European Journal of Cancer,* Vol. 43, No. 18, (December 2007), pp.2722-

Marulli, G., Rea, F., Nicotra, S., Favaretto, A.G., Perissinotto, E., Chizzolini, M., Vianello, A., & Braccioni, F. (2010). Effect of induction chemotherapy on lung function and exercise capacity in patients affected by malignant pleural mesothelioma. *European Journal of* 

Nowak, A., Byrne, M.J., Williamson, R., Ryan, G., Segal, A., Fielding, D., Mitchell, P., Musk, A.W., & Robinson, B.W. (2002). A multicentre phase II study of cisplatin and gemcitabine for malignant mesothelioma. *British Journal of Cancer*, Vol. 87, No. 5,

Opitz, I., Kestenholz, P., Lardinois, D., Muller, M., Rousson, V., Schneiter, D., Stahel, R., & Weder, W. (2006). Incidence and management of complications after neoadjuvant chemotherapy followed by extrapleural pneumonectomy for malignant pleural mesothelioma. *European Journal of Cardiothoracic Surgery,* Vol. 29, No. 4, (April 2006), pp.

*Cardiothoracic Surgery,* Vol. 37, No. 6, (June 2010), pp. 1464-1469.

Group (SWOG 9810). *Lung Cancer,* Vol. 60, No. 2, (May 2008), pp. 259-263

*Journal of Clinical Oncology,* Vol. 27, No. 18, (June 2009), pp. 3007-3013

Vol. 16, No. 6, (June 2005), pp. 923-927

(August 2002), pp. 491-496

No. 4, (May 2006), pp. 289-295, ISSN 1556-0864/06/0104-0289

620-626

8.

579-584


Malignant Pleural Mesothelioma: A Phase II Trial. *Journal of Thoracic Oncology.* Vol. 1, No. 4, (May 2006), pp. 289-295, ISSN 1556-0864/06/0104-0289

Flores, R.M., Pass, H.I., Seshan, V.E., Dycoco, J., Zakowski, M., Carbone, M., Bains, M.S., & Rusch, V.W. (2008). Extrapleural pneumonectomy versus pleurectomy/decortication in the surgical management of malignant pleural mesothelioma: results in 663 patients. *Journal of Thoracic and Cardiovascular Surgery,* Vol. 135, No. 3, (March 2008), pp. 620-626

116 Malignant Mesothelioma

pp. 25-30.

226

P3.302

2791-2797.

Vol.18, No.3, (July 2007), CD 006157

(February 2008), pp. 370-373

Burdett, S., Stewart, L.A., & Rydzewska, L. (2007). Chemotherapy and surgery versus surgery alone in non-small cell lung cancer. *Cochrane database of systematic reviews,* 

Byrne, M.J., Davidson, J.A., Musk, A.W., Dewar, J., van Hazel, G., Buck, M., de Klerk, N.H., & Robinson, B.W. (1999). Cisplatin and gemcitabine treatment for malignant mesothelioma: a phase II study. *Journal of Clinical Oncology,* Vol.17, No 1, (January 1999),

Cao, C.Q., Yan, T.D., Bannon, P.G., & McCaughan, B.C. (2010). A systematic review of extrapleural pneumonectomy for malignant pleural mesothelioma. *Journal of Thoracic Oncology,* Vol.5, No.10, (October 2010), pp.1692-1703, ISSN 1556-0864/10/0510-1692 Castagneto, B., Zai, S., Dongiovanni, D., Muzio, A., Bretti, S., Numico, G., Botta, M., & Sinaccio, G. (2005). Cisplatin and gemcitabine in malignant pleural mesothelioma: a phase II study. *American Journal of Clinical Oncology,* Vol. 28, No. 3, (June 2005), pp. 223-

Castagneto, B., Botta, M., Aitini, E., Spigno, F., Degiovanni, D., Alabiso, O., Serra, M., Muzio, A., Carbone, R., Buosi, R., Galbusera, V., Piccolini, E., Giaretto, L., Rebella, L., & Mencoboni,M. (2008). Phase II study of pemetrexed in combination with carboplatin in patients with malignant pleural mesothelioma (MPM). *Annals of Oncology,* Vol.19, No. 2,

Ceresoli, G.L., Zucali, P.A., Favaretto, A.G., Grossi, F., Bidoli, P., Del Conte, G., Ceribelli, A., Bearz, A., Morenghi, E., Cavina, R., Marangolo, M., Parra, H.J., & Santoro, A. (2006). Phase II study of pemetrexed plus carboplatin in malignant pleural mesothelioma.

de Perrot, M., Feld, R., Cho, B.C.J., Bezjak, A., Anraku, M., Burkes, R., Roberts, H., Tsao, M.S., Leighl, N., Keshavjee, S., & Johnston, M.R. (2009). Trimodality Therapy With Induction Chemotherapy Followed by Extrapleural Pneumonectomy and Adjuvant High-Dose Hemithoracic Radiation for Malignant Pleural Mesothelioma. *Journal of* 

Emri, S., Hurmuz, P., Kadilar, C., Cangir, A.K., Zorlu, F., Dogan, R., & Akyol, F. (2011). Pemetrexed-carboplatin doublets showed better mediab survival than pemetrexed-cisplatin in the treatment of Turkish malignant pleural mesothelioma patients. *Journal of Thoracic Oncology,* Vol. 6, No.6 (S2), (June 2011), pp. S 1671, Abtract n°

Favaretto, A.G., Aversa, S.M.L, Paccagnella, A., De Pangher Manzini, V., Palmisano, V., Oniga, F., Stefani, M., Rea, F., Bortolotti, L., Loreggian, L., & Monfardini, S. (2003). Gemcitabine Combined with Carboplatin in Patients with Malignant Pleural Mesothelioma. A Multicentric Phase II Study. *Cancer,* Vol. 97, No. 11, (June 2003), pp.

Flores, R.M., Krug, L.M., Rosenzweig, K.E., Venkatraman, E., Vincent, A., Heelan, R., Akhurst, T., & Rusch, V.W. (2006). Induction Chemotherapy, Extrapleural Pneumonectomy, and Postoperative High-Dose Radiotherapy for LocallyAdvanced

*Journal of Clinical Oncology,* Vol. 24, No. 9, (March 2006), pp. 1443-1448

*Clinical Oncology,* Vol. 27, No. 9, (March 2009), pp. 1413-1418


Pasello, G., Marulli, G., Nicotra, S., Rea, F., Loreggian, L., Bonanno, L., & Favaretto, A.G. (2011). Pemetrexed/Carboplatin or Pemetrexed/Cisplatin as first line treatment of malignant pleural mesotelioma (MPM): tolerability and response rate in operable patients. *Journal of Thoracic Oncology,* Vol. 6, No.6 (S2), (June 2011), pp. S1367, Abtract n° P3.297

Neoadjuvant Chemotherapy in Malignant Pleural Mesothelioma 119

Sugarbaker, D.J., Flores, R.M., Jaklitsch, M.T., Richards, W.J., Strauss, G.M., Corson, J.M., DeCAmp, M.M., Swanson, S.J., Bueno, R., Lukanich, J.M., Baldini, E.H., Mentzer, S.J. Resection margins, extrapleural nodal status, and cell type determine postoperative long-term survival in trimodality therapy of malignant pleural mesothelioma: results in 183 patients. (1999). *Journal of Thoracic and Cardiovascular Surgery,* Vol. 117, N0. 1,

Treasure, T., Tan, C., Lang-Lazdunski, L., & Waller, D. (2006). The MARS trial: mesothelioma and radical surgery. *Interactive Cardiovascular and Thoracic Surgery,* Vol. 5,

Treasure, T., Waller, D., Tan, C., Entwisle, J., O'Brien, M., O'Byrne, K., Thomas, G., Snee, M., Spicer, J., Landau, D., Lang-Lazdunski, L., Bliss, J., Peckitt, C., Rogers, S., Marriage, E., Coombes, G., Webster-Smitt, M., & Peto, J. (2009). The Mesothelioma and Radical Surgery Randomized Controlled Trial. The MARS feasibility study. *Journal of Thoracic* 

Treasure, T., Lang-Lazdunski, L., Waller, D., Bliss, J.M., Tan, C., Entwisle, J., Snee, M., O'Brien, M., Thomas, G., Senan, S., O'Byrne, K., Kilburn, L.S., Spicer, J., Landau, D., Edwards, J., Coombes, G., Darlison, L., & Peto, J. (2011). Extra-pleural pneumonectomy versus no extra-pleural pneumonectomy for patients with malignant pleural mesothelioma: clinical outcomes of the Mesothelioma and Radical Surgery (MARS) randomised feasibility study. *Lancet Oncology*, Vol. 12, No. 8, (August 2011), pp.

Van Meerbeeck, J.P., Gaafar, R., Manegold, C., Van Klaveren, R.J., Van Marck, E.A., Vincent, M., Legrand, C., Bottomley, A., Debruyne, C., & Giaccone, G. (2005). Randomized phase III study of cisplatin with or without raltitrexed in patients with malignant pleural mesothelioma: an intergroup study of the European Organisation for Research and Treatment of Cancer Lung Cancer Group and the National Cancer Institute of Canada.

Van Schil, P.E., Bass, P., Gaafar, R., Maat, A.P., Van de Pol, M., Hasan, B., Klomp, H.M., Abdelrahman, A.M., Welch, J., & van Meerbeeck, J.P. (2010). Trimodality therapy for malignant pleural mesothelioma: results from an EORTC phase II multicentre trial.

Vogelzang, N.J., Rusthoven, J.J., Symanoski, J., Denham, C., Kaukel, E., Ruffie, P., Gatzemeier, U., Boyer, M., Emri, S., Manegold, C., Niyikiza, C. & Paoletti, P. (2003). Phase II Study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma. *Journal of Clinical Oncology,* Vol. 21, No.

Weder, W., Kestenholz, P., Taverna, C., Bodis, S., Lardinois, D., Jerman, M., & Stahel, R. (2004). Neoadjuvant chemotherapy followed by extrapleural pneumonectomy in malignant pleural mesothelioma. *Journal of Clinical Oncology,* Vol. 22, No. 17, (September

*Journal of Clinical Oncology,* Vol. 23, No. 28, (October 2005), pp. 6881-6888

*European Respiratory Journal,* Vol. 36, No. 6, (June 2010), pp. 1362- 1369

(January 1999), pp. 54-63

763-772

No. 1, (January 2006), pp.58-59

14, (July 2003), pp. 2636-2644

2004), pp. 3451-3457

*Oncology,* Vol. 4, No. 10, (October 2009), pp. 1254-1258


Sugarbaker, D.J., Flores, R.M., Jaklitsch, M.T., Richards, W.J., Strauss, G.M., Corson, J.M., DeCAmp, M.M., Swanson, S.J., Bueno, R., Lukanich, J.M., Baldini, E.H., Mentzer, S.J. Resection margins, extrapleural nodal status, and cell type determine postoperative long-term survival in trimodality therapy of malignant pleural mesothelioma: results in 183 patients. (1999). *Journal of Thoracic and Cardiovascular Surgery,* Vol. 117, N0. 1, (January 1999), pp. 54-63

118 Malignant Mesothelioma

P3.297

Pasello, G., Marulli, G., Nicotra, S., Rea, F., Loreggian, L., Bonanno, L., & Favaretto, A.G. (2011). Pemetrexed/Carboplatin or Pemetrexed/Cisplatin as first line treatment of malignant pleural mesotelioma (MPM): tolerability and response rate in operable patients. *Journal of Thoracic Oncology,* Vol. 6, No.6 (S2), (June 2011), pp. S1367, Abtract n°

Rea, F., Marulli, G., Bortolotti, L., Breda, C., Favaretto, A.G., Loreggian, L., & Sartori, F. (2007). Induction chemotherapy, extrapleural pneumonectomy (EPP) and adjuvant hemi-thoracic radiation in malignant pleural mesothelioma (MPM): Feasibility and

Rea, F., Favaretto, A.G., Marulli, G., Spaggiari, L., De Pas, T.M., Ceribelli, A., Paccagnella, A., Crivellari, G., Russo, F., Ceccarelli, M., & Facciolo, F. (2011). *Journal of Clinical* 

Rice, D.C., Stevens, C.W., Correa, A.M., Vaporciyan, A.A., Tsao, A., Forster, K.M., Walsh, G.L., Swisher, S.G., Hofstetter, W.L., Mehran, R.J., Roth, J.A., Liao, Z., & Smythe, W.R. Outcomes after extrapleural pneumonectomy and intensity-modulated radiation therapy for malignant pleural mesothelioma. (2007) *Annals of Thoracic Surgery,* Vol. 84,

Rosell, R., Gòmez-Codina, J., Camps, C., Maestre, J., Padille, J., Canto, A., Mate, J.L., Li, S., Roig, J., Olazabal, A., Canela, M., Ariza, A., Skacel, Z., Morera-Prat, J., & Abad, A. (1994). A randomized trial comparing preoperative chemotherapy plus surgery with surgery alone in patients with non-small-cell lung cancer. *New England Journal of* 

Roth, J.A., Fossella, F., Komaki, R., Ryan, M.B., Putnam, J.B.J., Lee, J.S., Dhingra, H., De Caro, L., Chasen, M., Mc Gavran, M., Atkinson, E.N., & Hong, W.K. (1994). A Randomized Trial Comparing Perioperative Chemotherapy and Surgery With Surgery Alone in Resectable Stage IIIA Non-Small-Cell Lung Cancer. *Journal of National Cancer Institute,* 

Rusch, V.W., Rosenzweig, K., Venkatraman, E., Leon, L., Raben, A., Harrison, L., Bains, M.S., Downey, R.J., & Ginsberg R.J. (2001). A phase II trial of surgical resection and adjuvant high-dose hemithoracic radiation for malignant pleural mesothelioma. *Journal of Thoracic and Cardiovascular Surgery,* Vol. 122, No. 4, (October

Song W.A., Zhou N.K., Wang W., Chu X.Y., Liang C.Y., Tian X.D., Guo J.T., Liu X., Liu Y., Dai W.M. Survival benefit of neoadjuvant chemotherapy in non-small cell lung cancer: an updated meta-analysis of 13 randomized control trials. *J Thorac Oncol.* Vol..5, No 4:

Stewart, D.J., Martin-Ucar, A.E., Edwards, J.G., West, K., & Waller, D.A. (2005). Extrapleural pneumonectomy for malignant pleural mesothelioma: the risks of induction chemotherapy, right-sided procedures and prolonged operations. *European Journal of* 

*Cardio-thoracic Surgery,* Vol. 27, No. 3, (March 2005), pp. 373-378

results. *Lung Cancer,* Vol. 57, No. 1, pp. 87-95

*Oncology,* Vol. 29, Abstract 7090

No. 5, (November 2007), pp. 1692-1693

Vol. 86, No. 9, (May 1994), pp.673-680

2011), pp. 788-795

pp. 510-6.

*Medicine,* Vol. 330, No. 3, (January 1994), pp. 153-158


Weder, W., Stahel, R.A., Bernahrd, J., Bodis, S., Vogt, P., Ballabeni, P., Lardinois, D., Betticher, D., Schmid, R., Stupp, R., Ris, H.B., Jermann, M., Mingrone, W., Roth, A.D., & Spiliopoulos, A. (2007). Multicenter trial of neo-adjuvant chemotherapy followed by extrapleural pneumonectomy in malignant pleural mesothelioma. *Annals of Oncology,*  Vol. 18, No. 7, (July 2007), pp.1196-1202

Vol. 18, No. 7, (July 2007), pp.1196-1202

Weder, W., Stahel, R.A., Bernahrd, J., Bodis, S., Vogt, P., Ballabeni, P., Lardinois, D., Betticher, D., Schmid, R., Stupp, R., Ris, H.B., Jermann, M., Mingrone, W., Roth, A.D., & Spiliopoulos, A. (2007). Multicenter trial of neo-adjuvant chemotherapy followed by extrapleural pneumonectomy in malignant pleural mesothelioma. *Annals of Oncology,* 
