**Meet the editors**

Dr. Carmen Belli (MD., PhD.) is an oncologist working at San Raffaele Hospital in Milan, Italy. She has been actively involved in the clinical research with particular focus on mesothelioma, lung cancer, pancreatic and breast cancer. She collaborated with Italian Mesothelioma Group (Gi.Me) and had been an advisor to Buzzi Foundation in drafting research projects and clinical trials

on malignant mesothelioma. She also wrote a chapter titled "Mesotelioma Pleurico (Pleural Mesothelioma)" in the book "Medicina Interna Sistematica" of Claudio Rugarli (Elsevier/Masson, 6th Ed.), a standard text-book for the students of Internal Medicine in Italy. Recently, she is more focused on pancreatic cancer and is particularly involved in studying the role of diabetic condition and hyperinsulinism in progression of pancreatic tumors. She is also following several clinical trials testing new drugs in pancreatic cancer, alone or in combination with chemotherapy.

Santosh Anand (MSc.) is a senior bioinformatician at San Raffaele Scientific Institute in Milan, Italy. He has double Master's degree in Physics (IIT Kanpur, India) and in Computer Science (University of Nice, France), respectively, and has extensive experience in interdisciplinary and translational research. His main research interest is in integration and analysis of different kinds of

biological data (genomics, proteomics, NGS) to understand the molecular basis of genetic diseases. He is particularly interested in biomarker studies and has worked on biomarkers for lung cancer, fabry disease and pancreatic cancer. Currently he is involved in several clinical and basic research projects in type-I diabetes (T1D). These include finding ways to increase the efficacy of bone marrow islet transplant (in T1D pts.) and (pre-clinical) stem cell therapy; and dissecting the roles of neutrophil, Teff and Treg cells in T1D. In the past, he worked as bioinformatician at Telethon Institute of Genetics and Medicine (Naples, Italy) and managed and analyzed all the data of EU integrated project EURExpress.

Contents

**Preface VII** 

Rossella Galati

Chapter 5 **Neoadjuvant Chemotherapy in** 

Chapter 1 **Mineralogy and Malignant Mesothelioma: The South African Experience 1** 

Chapter 2 **Effect of Asbestos on Anti-Tumor Immunity** 

Takumi Kishimoto and Takemi Otsuki

**in Malignant Mesothelioma 49** 

**and Immunological Alteration in Patients with Malignant Mesothelioma 31** 

Chapter 3 **Role of Inflammation and Angiogenic Growth Factors** 

Chapter 4 **The Role of Cyclooxygenase-2, Epidermal Growth Factor** 

**Malignant Pleural Mesothelioma 93**  Giulia Pasello and Adolfo Favaretto

James I. Phillips, David Rees, Jill Murray and John C.A. Davies

Yasumitsu Nishimura, Megumi Maeda, Naoko Kumagai-Takei, Hidenori Matsuzaki, Suni Lee, Kazuya Fukuoka, Takashi Nakano,

Loredana Albonici, Camilla Palumbo and Vittorio Manzari

**Receptor and Aromatase in Malignant Mesothelioma 79** 
