**1. Introduction**

The population of the elderly is increasing worldwide. India is going to be the highest in Asia with people aged 60 years and above. In 2020, there are an estimated 727 million persons aged 65 years or above worldwide. It may be doubled by 2050, nearing to more than 1.5 billion persons. The share of older persons in the global population is expected to increase from 9.3 percent in 2020 to 16.0 percent in 2050 [1]. As age advances, they are more exposed to multiple diseases in addition to the increased incidence of other illnesses such as Alzheimer's disease, Parkinson's disease, vascular dementia, stroke, arthritis, and fractures [2]. So, medications play a crucial role in geriatric health care as they treat chronic diseases, reduce pain, and improve quality of life [3].

The physiological changes that occur with aging alter the pharmacokinetics and pharmacodynamics of drugs, which increases the risk the adverse drug reactions (ADR) and drug interactions (DI). Multi-prescription, polytherapy, and inappropriate medication use also increase the incidence of ADR. A major threat to the healthrelated quality of life of older adults is ADRs. They can decrease functional status and increase the use of health services and costs, as well as mortality [4]. Hence this

article focuses on the prevalence and risk factors for ADR in older adults and the steps taken to minimize them.
