**2. Signal exposition**

Before we dive into the process of signal management, it is essential we understand a few terminologies. Starting with the most basic of all: signal.

A *signal*, according to WHO, is reported information on a possible causal between an adverse effect and a drug, the relationship being unclear or incompletely documented previously. It is important to note that a signal is not a verified opinion but a hypothesis-generating situation that must be validated [3].
