**Abstract**

Plants are the storage place for many active ingredients that are currently used in pharmaceuticals. Proofs have been expanded for ages to indicate the profitable capacity of medicinal plants used in various infections, especially for cancer treatment. The plants, *Chromolaena odorata* (Family Asteraceae), *Croton oblongifolius* Roxb. (Family Euphorbiaceae), *Tinospora cordifolia* (Family Menispermaceae), *Melastoma malabathricum* L. (Family Melastomaceae), and *Dioscorea bulbifera* (Family Dioscoreaceae) have been used for a long time in Myanmar's traditional medicine. This study aimed to review systematically the cytotoxic activity of the whole plants and their extracts, fractions, and isolated compounds from these selected medicinal plants. This chapter also be substantiated for additional analysis on phytochemical constituents and pharmacological action of therapeutic plants species in Myanmar.

**Keywords:** cytotoxic activity, Myanmar, medicinal plants, isolated compounds, secondary metabolite
