*Cardiac Amyloidosis DOI: http://dx.doi.org/10.5772/intechopen.109522*

and syncopal events. However, many factors may contribute to syncope such as postural hypotension due to excessive diuresis or autonomic neuropathy and small ventricular cavities. Low blood pressure is a common finding and not necessarily accompanied by orthostatic hypotension. It has long been known that syncope is common in AL amyloid heart disease and mostly precipitated by physiologic stress. Stress-precipitated syncope is associated with a poor prognosis in such patients, both in terms of their median survival (2 months) and as a common precursor of sudden cardiac death [32]. Additionally, autonomic dysfunction in these patients is associated with decreased cardiac output. However, there is no evident association between syncopal events and mortality in ATTR patients despite frequent events and poor quality of life [37, 38].
