**8. Conclusions**

The cornerstone for the modern treatment of paroxysmal atrial fibrillation (AF) is pulmonary vein isolation, also called an AF ablation. Various ablation technologies exist to accomplish this goal with specific advantages. Upfront ablation strategies have been shown superior to AAD in certain patient populations. One unique ablation technology for pulmonary vein isolation is Cryoablation. Clinical trial data shows both non-inferiority, and in some cases, superior outcomes of cryoablation to antiarrhythmic drug therapy and other ablation techniques. Cryoablation has been shown to be safe, and effective in various common anatomic configurations. An evolving technology, newer generation cryoballoons offer improved efficacy and continued safety.
