**7. Alternate uses/future directions**

Based on this biophysical characteristic of preserving the tissue architecture, cryoablation was preferred to reduce the risk of causing destruction to the normal structure during specific arrhythmias such as atrioventricular nodal reentrant tachycardia or tachycardia originating near the His bundle region. These characteristics explain the lower risk of cardiac perforation or thrombogenicity compared to RFA. Cryothermal energy is produced during refrigerants injected through a fine tube. The refrigerant vaporizes at the tip of a cryoablation catheter and can freeze the adjacent tissue. While freezing, the catheter tip adheres to the affected tissue, which enables the application of stable energy [41].

A high cooling power and culture with culture cryoablation also called Adagio combination of newly exploited cryogenically interchangeable stylette needles. Flexible continuous leak and creation of other tachyarrhythmia by optimizing her catheter shape. Patients who underwent AF ablation enrolled in this procedure in the assessment of the procedural data that was focused on safety comprising first-pass isolation and defined as a successful PVI after initial application. The studies follow sequential PV isolation using the Novell UL TC catheters to visit without compromising safety the first-pass isolation was accomplished about half of the PVs.
