*3.2.1 Esophageal squamous cell carcinoma*

Tang et al. explored the function of lncRNA LOC146880 in esophageal squamous cell carcinoma (ESCC) progression. The result of in vivo and in vitro experiments showed LOC146880 sponged miR-328-5p to regulate fascin actin-bundling protein 1 (FSCN1) activating MAPK signaling pathway, resulting in liver metastasis [123] (**Table 2**).
