**Abstract**

This chapter overviews palliative treatment modalities for patients with bone metastases. In the introduction section, the origin of bone metastases and complication of metastatic patients have been discussed. Then, the main body explains treatment modalities including pain relievers, bisphosphonates, surgery, external beam radiotherapy, and targeted radionuclide therapy for pain palliation of patients with bone metastases.

**Keywords:** bone metastases, pain palliation, palliative therapy
