**Funding**

This work was supported by funds from Faperj (Foundation for Research Support of the State of Rio de Janeiro, E-26/203.056/2017, E-26/010.001925/2015, E-26/311.264/2021, SEI-260003/002756/2022; Fopesq 2021/UFF; CNPq (National Research Council, 309611/2018-0); and FOCEM (Fundo para a Convergência Estrutural do MERCOSUL).

*Perspective Chapter: Breast-Tumor-Derived Bone Pre-Metastatic Disease – Interplay... DOI: http://dx.doi.org/10.5772/intechopen.107278*
