*3.2.1 Pleiotropic effects of statins in non-mesenchymal tumors*

Inhibition of mevalonate pathway by statins (**Table 2**) (**Figure 5**) [10] prevents Rho protein isoprenylation and consequently produces apoptosis [47], decreases cell proliferation [49] and tumor cells invasiveness [42], but not in non-tumoral cells [43].
