**6.3 Open biopsy**

Indicated when a large volume of tissue is needed for proper diagnosis or when a percutaneous biopsy cannot be safely performed. Incisional biopsy is performed along the planned path in case of resection of the neoplasm and with the smallest incision compatible with the procedure. Transverse incisions should be avoided because their resection with a contaminated path during the treatment of the neoplasm, in addition to requiring a greater volume of excised tissue, can compromise the preservation of the limb. The formation of bruises and the use of drains that can contaminate the soft tissues should be avoided. The disadvantages of incisional biopsy are the possibility of contamination of soft tissues, complications with the operative wound, and is a more expensive procedure compared to percutaneous procedures [48].
