**5. Conclusion**

Mycotoxins are secondary fungi metabolites present in foods which can cause adverse effects on humans and animals. Therefore, it is essential to develop a simple, effective, sensitive and validated analytical method to monitor mycotoxins. Sample preparation is an important step in the analysis of mycotoxins and other contaminants from complex food matrices. And due to the growing demand for high-throughput multiresidue methods (MRM), researchers have developed several easy to perform sample treatment methods, which are rapid and of low cost, require a minimum volume of solvents, provide a high selectivity without complicated clean-up solutions, and allow analysis of broad range of analytes. QuEChERS is fast and simple analytical method which has been developed and optimized for the analysis of a fast and simple analytical method, although several researchers have over the years modified the original QuEChERS technique, which allow multiresidue analysis.

Most of the QuEChERS methods described in this review were couple to liquid chromatography analysis. This is partly due to the great increases in its sensitivity and selectivity, which has led to a significant contribution in qualitative and quantitative determination of mycotoxins in cereals and related foodstuffs. Also, the increasing use of hybrid mass spectrometers, incorporating mass analyzers that are capable of high mass resolution and accurate mass measurements, mitigates some of the problems associated with selectivity and identification. The improvement and upgrading of the available techniques will determine the effectiveness and efficiency of mycotoxins analysis in food matrices.
