**8. Conclusion**

With Ovarian cancer being the 8th most common cancer among women globally, and one of the most complex diseases with multiple types each having distinct aetiology, risk factors and distinct response to treatment, tremendous progress has been so far recorded in understanding the molecular profiles of each type as well as the role played by *TP53* mutation in the development and progression of ovarian cancers. Also, understanding epidemiology, histopathology, and hereditary susceptibility are of equal importance.

Therefore, further molecular and biochemical studies that will explain detailed mechanisms underlying the role of the mutant *TP53* in ovarian cancer development and progression, especially the high-grade serous ovarian carcinoma are

recommended. More so, further studies on the *TP53* mutation types will favour the development of the right therapeutic interventions for ovarian cancers.
