**2. Description of molecular profiles**

Recently, ovarian cancers have been classified into type 1 and type 2 tumours. Type 1 constitutes of low-grade tumours (mucinous, endometrioid, low-grade

serous and clear cell types) that harbour mutations in *PTEN, KRAS* and *BRAF* with microsatellite instability and are thought to originate from the ovary. While type 2 tumours are high-grade serous and carcinosarcomas that originate from the fallopian tube and have mutations in *BRCA1, BRCA2* and *TP53* [6–8].

Whole-exome and Whole-genome sequencing studies of ovarian cancer have not only revealed its genetic heterogeneity, but have identified the genomic effect of aberrant DNA damage and repair processes in endometrioid, high-grade serous, and clear cell ovarian cancers [9].
